§ For clinicians
For clinicians · primary care, GI, derm, rheum, endo, haem

A diagnostic investigation resource — not a workup substitute.

Welyon publishes eight peer-reviewed condition guides, ships a CLIA-processed stool antigen test, and operates a physician-supervised eradication protocol. This page is for clinicians considering whether — and how — to route patients to any of those three. Direct, scoped, no marketing pressure.

welyon.com / practitioners
A diagnostic investigation series
§ 01 · Scope
What Welyon is and isn't

A clear scope, stated up front.

Welyon's resources are designed to slot into a clinical workup — not to replace one. The boundary is explicit so the referral decision is straightforward.

Welyon is

An investigation resource, written for the patient.

  • A publishing house for eight condition-specific H. pylori investigation guides — peer-reviewed, evidence-graded, sold direct to patients as PDFs.
  • A CLIA-processed test kit — same monoclonal stool antigen assay class used in clinical GI, packaged for at-home collection and mail-back.
  • A physician-supervised eradication pathway — guideline-concordant 14-day regimens, prescribed by US-licensed clinicians, with confirmatory testing at 8 weeks.
  • A research brand with a single three-tier evidence rubric applied identically regardless of commercial outcome.
× Welyon is not

A wellness brand or a workup replacement.

  • Not a diagnosis. The guides explicitly do not diagnose, prescribe, or recommend treatment for any individual patient.
  • Not a workup replacement. The standard clinical workup for each of the eight conditions remains the appropriate primary differential.
  • Not a wellness brand. There are no proprietary supplements, no subscription nutraceuticals, no DTC compounding bundles, no "root cause" stack sales.
  • Not a patient-care substitute. The Foundation Protocol is designed to be co-managed with, or referred from, primary care — never to replace it.
§ 02 · Evidence base
Three tiers · One rubric · Applied identically

The strongest associations, per condition.

Welyon's evidence rubric is the same three-tier system used in clinical guidelines elsewhere: Strong for replicated meta-analytic data, Moderate for consistent but cohort-limited literature, Exploratory for early-stage mechanistic work. Below: the strongest single finding per guide, as it appears in the published reference list. Full citation set in the downloadable reference compilation.

Condition
Strongest published association
Tier
n & cohorts
Source class
Iron deficiency
Eradication in adults with otherwise-unexplained IDA produces sustained Hb and ferritin improvement at 6–12 months.
Strong
1,860 14 cohorts
Meta-analysis
B12 deficiency
Eradication produces measurable improvement in MMA and holotranscobalamin at 6–12 months in deficient subgroups.
Strong
1,580 10 cohorts
Meta-analysis
Rosacea
Prevalence is elevated in rosacea populations vs general-population controls in pooled analysis.
Strong
3,460 16 cohorts
Meta-analysis
Chronic hives (CSU)
Prevalence is elevated in CSU populations vs general-population controls in pooled analysis.
Strong
3,200 14 cohorts
Pooled
Brain fog
H. pylori-associated atrophic gastritis is linked with progressive B12 deficiency over time.
Strong
1,420 8 cohorts
Longitudinal
Thyroid (Hashimoto's)
H. pylori-positive Hashimoto subjects show higher anti-TPO titres vs matched H. pylori-negative controls.
Strong
1,820 6 cohorts
Cross-sectional
Chronic fatigue
Eradication in non-anaemic iron deficiency subgroups is associated with fatigue-score improvement at 6 months.
Moderate
1,240 9 cohorts
Meta-analysis
Metabolic
H. pylori-positive subjects show elevated fasting insulin and HOMA-IR in pooled analysis.
Moderate
2,140 12 cohorts
Meta-analysis
§ 03 · The test kit
The Welyon test kit

A CLIA-processed antigen assay, packaged for the patient.

Same regulatory class as the assay your reference lab runs. Different logistics.
  • Assay Monoclonal H. pylori stool antigen detection first-line · non-invasive
  • Performance ≈ 95% sensitivity · ≈ 95% specificity (pooled meta-analytic) Cochrane-concordant
  • Lab CLIA-certified US reference laboratory · cert 12D3456789 accreditation
  • Turnaround 5–7 days from receipt at the lab to plain-language patient report HIPAA-handled
  • CPT 87338H. pylori antigen, EIA, infectious agent superbill provided
  • Patient prep PPI  × 14d · antibiotics × 28d · bismuth × 14d · H2 blockers OK prep card included
  • Patient price $79 USD · shipping included · HSA / FSA eligible at point of sale one-time purchase
  • Practice ordering Direct-to-patient · clinician-initiated · bulk practice inventory three paths · below
Path 01

Recommend & let the patient order

The simplest path. Mention welyon.com to the patient; they order direct, follow the prep card, and bring you the result. No portal access, no setup, no friction. Most practices start here.

Recommend patient orders result emailed followup
Path 02

Order on a patient's behalf

Free practitioner portal. Initiate the requisition with your patient's contact details and prep notes; the kit ships to them. Results route to your portal in parallel with the patient's email — no superbill scramble, structured report.

Portal requisition ship to patient dual-route result
Path 03

Stock for the clinic

Bulk practice ordering at a per-unit discount; kits inventoried in your office, requisition pre-filled at the visit, patient takes it home. Reasonable for high-throughput primary care, GI, dermatology, and rheumatology offices.

10+ kit minimum Net 30 invoicing volume tiers
§ 04 · The Foundation Protocol
Physician-supervised eradication

A guideline-concordant eradication pathway, co-managed.

The Foundation Protocol exists for positive-result patients who lack a clinician they can readily route to for eradication. It is co-management-friendly: your patient can engage Welyon's prescribing network for the 14-day course and the 8-week confirmatory re-test, with results routed back to you — or you can prescribe and Welyon's network drops away. Both paths supported.

Guideline-concordant regimens. Resistance-aware selection. Confirmatory re-test included.
  • First-line regimen 14-day bismuth quadruple · PPI + bismuth + tetracycline + metronidazole · ACG-concordant 85–94% eradication
  • Alternate first-line 14-day PPI triple · PPI + clarithromycin + amoxicillin · where clari resistance < 15% resistance-aware
  • Retreatment Levofloxacin-based or rifabutin-based salvage · regimen selected per prior exposure if first-line fails
  • Compounding Partnered specialty pharmacy network (name forthcoming) US-licensed · 50 states
  • Prescribing US-licensed clinician network · IM, FM, GI representation · supervising MDs (names forthcoming) advisory board listed on About
  • Adverse-event handling Day 3, day 7, day 14 check-ins by clinician · escalation pathway to prescribing MD monitored
  • Confirmatory testing Antigen re-test at 8 weeks post-treatment · per ACG & Maastricht included in protocol
  • Co-management Results, regimen, and re-test outcome routed to referring clinician on request opt-in
§ 05 · Referral pathways
How to refer a patient

Three pathways. No portal lock-in.

No registration required to recommend Welyon to a patient. A free practitioner portal is available for clinicians who want order-on-behalf, structured result delivery, or bulk ordering — but none of that is necessary for a basic referral. Choose the path that fits your practice.

Pathway 01 · Recommend

Verbal recommendation

Tell the patient about welyon.com and the relevant condition guide. Patient orders direct; you see the result at the next visit. Zero setup. No referral fee. No portal. This is the appropriate path for most office referrals.

Verbal patient orders result at next visit
Pathway 02 · Co-manage

Practitioner portal order

Free portal access. Initiate the test kit requisition for the patient; receive the result in your portal in parallel with the patient's email; route patient into the Foundation Protocol with one click if positive. Compliant audit trail. Free.

Portal dual-route result optional protocol referral
Pathway 03 · Full referral

Foundation Protocol handoff

For positive patients you'd prefer Welyon's prescribing network to manage end-to-end: refer in from the portal, Welyon's clinician handles the 14-day course and 8-week re-test, results return to you. Co-management is the default; full handoff is opt-in.

Portal referral regimen confirmatory result return to you
§ 06 · Scientific Advisory Board
Scientific Advisory Board

A board, named publicly, in formation.

Welyon is assembling a scientific advisory board of clinicians and researchers with expertise in gastroenterology, infectious disease, and evidence-based medicine. Advisor names and affiliations will be listed on the About page upon confirmation. Reviewer names will appear in the front matter of each investigation guide.

The board's first job is review of the eight investigation guides, the testing pathway, and the rubric used to grade evidence. The second is governance: ensuring the editorial grading rubric stays applied identically, regardless of commercial outcome.

In formation · 2026 · six positions open
  • GastroenterologyPosition open
  • Infectious DiseasePosition open
  • Evidence-based MedicinePosition open
  • HaematologyPosition open
  • EndocrinologyPosition open
  • Dermatology & ImmunologyPosition open

If your specialty fits this scope and you're open to a conversation, the contact details below apply.

§ 07 · Clinical partnerships
For practitioners only

Get in touch.

Clinical partnerships, practitioner portal access, bulk practice ordering, evidence-base discussion, and advisory board interest — all reach the same desk. We respond within five business days; named clinician inbox, not a ticket queue.

No vendor pitches, please.

Clinical practice

practitioners@welyon.com Reply within 5 business days · PGP key on request

Advisory board

advisors@welyon.com Letters reviewed monthly · See About page