For clinicians · primary care, GI, derm, rheum, endo, haem
A diagnostic investigation resource — not a workup substitute.
Welyon publishes eight condition guides grounded in peer-reviewed research, ships a CLIA-processed stool antigen test, and is developing a physician-supervised protocol. This page is for clinicians considering whether — and how — to route patients to any of those three. Direct, scoped, no marketing pressure.
Welyon's resources are designed to slot into a clinical workup — not to replace one. The boundary is explicit so the referral decision is straightforward.
✓ Welyon is
An investigation resource, written for the patient.
A publishing house for eight condition-specific H. pylori investigation guides — evidence-graded and grounded in peer-reviewed research, sold direct to patients as PDFs.
A CLIA-processed test kit — same monoclonal stool antigen assay class used in clinical GI, packaged for at-home collection and mail-back.
A physician-supervised protocol — in development.
A research brand with a three-tier evidence rubric applied identically regardless of commercial outcome.
× Welyon is not
A wellness brand or a workup replacement.
Not a diagnosis. The guides explicitly do not diagnose, prescribe, or recommend treatment for any individual patient.
Not a workup replacement. The standard clinical workup for each of the eight conditions remains the appropriate primary differential.
Evidence-first by design. Every claim follows the peer-reviewed literature, graded and disclosed.
§ 02 · Evidence base
Three tiers · One rubric · Applied identically
The strongest associations, per condition.
Welyon's evidence rubric is the same three-tier system used in clinical guidelines elsewhere: Strong for replicated meta-analytic data, Moderate for consistent but cohort-limited literature, Exploratory for early-stage mechanistic work. Below: the strongest single finding per guide, as it appears in the published reference list. Full citation set in the downloadable reference compilation.
Condition
Strongest published association
Tier
Cohorts
Source class
Iron deficiency
Eradication in adults with otherwise-unexplained IDA produces sustained Hb and ferritin improvement at 6–12 months.
Strong
1,860 14 cohorts
Meta-analysis
Immune / ITP
Eradication raises platelet counts in about half of H. pylori-positive ITP patients; testing is guideline-endorsed (ASH).
Strong
1,555 25 cohorts
Meta-analysis
Chronic fatigue
Eradication in non-anaemic iron-deficiency subgroups is associated with fatigue-score improvement at 6 months.
Moderate
1,240 9 cohorts
Meta-analysis
Brain fog
H. pylori-associated atrophic gastritis is linked with progressive B12 decline over time.
Moderate
1,420 8 cohorts
Longitudinal
Thyroid (Hashimoto's)
H. pylori-positive Hashimoto subjects show higher anti-TPO titres vs matched controls.
Moderate
1,820 6 cohorts
Cross-sectional
Nerve & energy (B12)
Eradication produces measurable improvement in MMA and holotranscobalamin at 6–12 months in deficient subgroups.
Moderate
1,580 10 cohorts
Meta-analysis
Skin / chronic hives
Prevalence is elevated in chronic-urticaria populations vs controls; eradication improves remission across pooled RCTs.
Moderate
3,200 14 cohorts
Pooled
Metabolic
H. pylori-positive subjects show elevated fasting insulin and HOMA-IR in pooled analysis; the association is consistent but causation is not established.
Exploratory
2,140 12 cohorts
Meta-analysis
§ 03 · The test kit
The Welyon test kit
A CLIA-processed antigen assay, packaged for the patient.
Same regulatory class as the assay your reference lab runs. Different logistics.
AssayMonoclonal H. pylori stool antigen detectionfirst-line · non-invasive
Patient priceSet at launch · shipping included · HSA / FSA eligible at point of saleone-time purchase
Practice orderingDirect-to-patient · clinician-initiated · bulk practice inventorythree paths · below
Path 01
Recommend & let the patient order
The simplest path. Mention welyon.com to the patient; they order direct, follow the prep card, and bring you the result. No portal access, no setup, no friction. Most practices start here.
Recommend → patient orders → result emailed → followup
Path 02
Order on a patient's behalf
Free practitioner portal (in development). Initiate the requisition with your patient's contact details and prep notes; the kit ships to them. Results route to your portal in parallel with the patient's email — no superbill scramble, structured report.
Portal requisition → ship to patient → dual-route result
Path 03
Stock for the clinic
Bulk practice ordering at a per-unit discount; kits inventoried in your office, requisition pre-filled at the visit, patient takes it home. Reasonable for high-throughput primary care, GI, dermatology, and rheumatology offices.
At launch: 10+ kit minimum → Net 30 invoicing → volume tiers
§ 04 · The Welyon HP Program
Physician-supervised eradication
A guideline-concordant eradication pathway, co-managed.
The Welyon HP Program is a physician-supervised intervention for confirmed-positive results. A licensed clinician reviews the patient's history, selects a regimen appropriate to local resistance patterns, and supervises the course end-to-end including post-treatment confirmatory testing. Currently in development.
§ 05 · Referral pathways
How to refer a patient
Three pathways. No portal lock-in.
No registration required to recommend Welyon to a patient. A free practitioner portal is available for clinicians who want order-on-behalf, structured result delivery, or bulk ordering — but none of that is necessary for a basic referral. Choose the path that fits your practice.
Pathway 01 · Recommend
Verbal recommendation
Tell the patient about welyon.com and the relevant condition guide. Patient orders direct; you see the result at the next visit. Zero setup. No referral fee. No portal. This is the appropriate path for most office referrals.
Verbal → patient orders → result at next visit
Pathway 02 · Co-manage
Practitioner portal order
Free portal access (in development). Initiate the test kit requisition for the patient; receive the result in your portal in parallel with the patient's email; route patient into the Welyon HP Program with one click if positive. Compliant audit trail. Free.
Portal → dual-route result → optional protocol referral
Pathway 03 · Full referral
Welyon HP Program referral
The Welyon HP Program is currently in development.
Portal referral → regimen → confirmatory result → return to you
§ 06 · Scientific Advisory Board
Scientific Advisory Board
A board, named publicly, in formation.
Welyon is assembling a scientific advisory board of clinicians and researchers with expertise in gastroenterology, infectious disease, and evidence-based medicine. Advisor names and affiliations will be listed on the About page upon confirmation. Reviewer names will appear in the front matter of each investigation guide.
The board's first job is review of the eight investigation guides, the testing pathway, and the rubric used to grade evidence. The second is governance: ensuring the editorial grading rubric stays applied identically, regardless of commercial outcome.
In formation · 2026 · six positions open
GastroenterologyPosition open
Infectious DiseasePosition open
Evidence-based MedicinePosition open
HaematologyPosition open
EndocrinologyPosition open
Dermatology & ImmunologyPosition open
If your specialty fits this scope and you're open to a conversation, the contact details below apply.
§ 07 · Clinical partnerships
For practitioners only
Get in touch.
Clinical partnerships, practitioner portal access, bulk practice ordering, evidence-base discussion, and advisory board interest — all reach the same desk. Named clinician inbox, not a ticket queue.