Not sure which guide is yours?
A free online introduction to the H. pylori diagnostic gap, the four systemic mechanisms by which it has been associated with non-digestive conditions, and the eight clinical presentations worth investigating. Written in clinical voice; every claim graded and cited.
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You were right to keep looking.
You're not imagining it. The workup just hasn't gone far enough yet.
What you'll understand after reading.
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i.
What H. pylori is — and why most carriers don't know they have it.
The basic biology, the prevalence (roughly 1 in 3 American adults), the reasons it stays clinically silent for years, and the implications of that silence for the conditions it has been associated with.
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ii.
Why standard workups miss the systemic connections.
A short history of the diagnostic gap — how the workup order sets settled around 'GI symptoms only', and what thirty years of peer-reviewed literature has done to that boundary since.
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iii.
The four mechanisms in plain language.
Hypochlorhydria · hepcidin / inflammation · nutrient malabsorption · molecular mimicry. One paragraph per mechanism, with the strength of the underlying evidence tagged transparently.
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iv.
Which eight conditions have peer-reviewed associations.
One paragraph per condition — fatigue, brain fog, iron, thyroid, metabolic, nerve & energy, skin, and immune — with the strongest published finding and the evidence tier inline.
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v.
What the three evidence tiers mean.
Strong, Moderate, Exploratory — what each threshold requires, why every claim across the series is tagged, and why exploratory findings are flagged on the cover instead of buried.
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vi.
What to do next — if you recognise your condition.
A short decision tree — by primary symptom, by lab pattern, by clinical context — that routes you to the condition-specific investigation guide, the testing kit, or back to your primary care physician.
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If you recognise your condition in the overview, there is a full investigation guide for it.
Each condition has its own thirty-to-forty page guide — mechanism, the standard workup's blind spot, the secondary labs to request, and the conversation script for your next appointment. The Overview tells you whether one applies. The guides go deep.
Recognise yourself in the list? Start with the overview.
One read tells you whether H. pylori is worth investigating for your condition — and which next step fits.
Send me the overview →