You were right to keep looking.
You're not imagining it. The workup just hasn't gone far enough yet.
Everything checked out. But you still don't feel like yourself.
- Your fasting insulin or blood glucose remains elevated despite consistent dietary changes
- You have been managing insulin resistance or metabolic syndrome for more than a year without resolution
- You experience hunger that feels disproportionate — never quite satisfied despite adequate meals
- Your metabolic numbers aren't responding the way they should to the work you're putting in
- Your workup has never investigated H. pylori as a possible upstream contributor
- You want to understand the mechanism before your next metabolic appointment
- Fasting insulin staying high despite consistent diet and exercise
- A HOMA-IR score above 2.0 with no clear dietary explanation
- Insulin resistance that creeps up even while you're cutting calories
- Hunger that feels out of proportion to what you eat
- Belly fat that's especially hard to shift despite cutting calories
- Appetite that doesn't settle after an adequate meal
- Still hungry even after eating enough
- Fullness that doesn't respond to dietary changes
- Metabolic struggles that feel hormonal rather than down to willpower
A workup for the metabolism that won't move.
This guide is written for the person whose labs say 'metabolic syndrome' but whose plan keeps stalling — diet, training, and sleep all in order, the numbers refusing to budge. It maps three ways an unsuspected H. pylori infection has been linked to insulin resistance, hunger hormones, and satiety — factors that can be working against you on top of diet and exercise.
It is not a treatment protocol. It's the investigation itself, written down — so your next move is far more specific than your last, whether you take it to a doctor or pursue it on your own.
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i.
The clinical signature of metabolic numbers that won't moveHow the picture differs from straightforward insulin resistance and fatty liver — and the questions that tell them apart.
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ii.
Three pathways the metabolic workup rarely checksInflammation blunting the insulin signal, hunger hormones knocked off balance, the "full" signal not getting through — with the evidence tier for each, honestly graded.
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iii.
Why an 'OK' HbA1c doesn't always mean an OK metabolismWhat a single headline number can obscure — and the markers worth reading alongside it.
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iv.
Labs to request beyond a basic metabolic panelFasting insulin, HOMA-IR, hs-CRP, fasting glucose — read together, before and after testing.
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v.
Testing options for H. pyloriStool antigen, urea breath test, biopsy — trade-offs, costs, and what each rules in or out.
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vi.
What positivity changesThe decisions that follow a positive result — eradication, metabolic re-test at 3 and 6 months, and realistic expectations for what clearing it can and can't do.
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vii.
A script for raising itA practical framework for discussing testing, interpretation, and next steps — whether with your physician or as a self-directed investigation.
Sharper thinking. Clearer next steps.
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Know exactly what to investigate next — and why an infectious contributor to insulin resistance slips through a standard metabolic workup.
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Understand the GLP-1 blind spot — why drugs like semaglutide manage the numbers downstream while an upstream cause goes unaddressed.
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Walk away with a specific plan to act on — with a doctor or on your own — including a metabolic baseline to track before and after.
Three tiers. One rubric. No exceptions.
Every claim is tagged Strong, Moderate, or Exploratory — so you can see exactly how solid each one is. The association is real but modest, and causation isn't established — here's the honest picture.
Metabolic syndrome · evidence summary
A few honest questions.
Is this medical advice?
No. This guide is educational — written to help you understand the evidence, evaluate testing options, and identify questions worth exploring with your healthcare team or on your own.
Why isn't my doctor already investigating this?
Metabolic medicine is organized around diet, exercise, and medication, and H. pylori is classified as a gastroenterological infection — so an infectious contributor to insulin resistance sits in the gap between specialties rather than in either one's routine workup. It's not a failing on your part. The guide explains the mechanism and exactly what to ask for — whether you raise it with a doctor or decide to pursue it yourself.
Do I need to buy the testing kit?
No — the guide is sold separately from any test or product. It covers all three testing options — stool antigen, urea breath test, biopsy — what each costs, and how to ask for it. But a test only tells you yes or no; the guide is what tells you which test to request and what to do with the result, which is where most people get stuck.
What if my labs are 'in range'?
The guide spends a section on this exact situation — what 'in range' obscures, what to look at in combination, and the secondary markers that frequently shift the picture without changing the headline numbers.
Refund policy?
14 days, no questions. If the guide isn't useful, the Lemon Squeezy receipt has a one-click refund link.
Who wrote it?
Researched, written, and medically reviewed by a physician on the Welyon team. Every claim is drawn from peer-reviewed literature and graded inline — Strong, Moderate, or Exploratory — so you can weigh the evidence behind each one yourself.
Start closing the gap between 'normal' and 'explained.'
Move from ruled out to figured out.
40 pages, nine citations, three pathways, one clearer next step.
Many readers find more than one guide applies. Each is sold separately — or ask about bundle pricing at checkout.